منابع مشابه
Bence Jones protein in primary systemic amyloidosis.
The recent population-based study by Kyle et al,’ which was the first to provide precise epidemiologic information about primary systemic amyloidosis, reported the demonstration of a monoclonal (M)protein in the serum or urine from 16 of 21 patients (76%) with amyloid of unequivocal Ig origin (AL). However, the number of patients in whom free monoclonal Ig light chain (ie, Bence Jones [BJ] prot...
متن کاملImmunoglobulin D myeloma and amyloidosis: immunochemical and structural studies of Bence Jones and amyloid fibrillar proteins.
Urinary Bence Jones protein and amyloid fibril protein isolated from the subcutaneous tissue of a patient with IgD myeloma and associated amyloidosis were subjected to physicochemical and immunochemical identification. Peptide maps and amino-terminal tetrapeptide composition obtained from the two proteins were comparable. Immunochemical cross-reactivity between the two proteins, with other lamb...
متن کاملMetabolism of Bence Jones Proteins.
Bence Jones proteins are molecules of about 40,000 mol wt present in the urine of many patients with plasma cell malignancy. These microglobulins, which are synthesized in plasma-cell tumors (1, 2), share many immunochemical and physicochemical features with the larger 6.6 S y-globulins. That Bence Jones proteins are similar to or identical with components of the larger y-globulins has been sug...
متن کاملRenal AA amyloidosis in a patient with Bence Jones proteinuria and ankylosing spondylitis.
A patient with a 10 year history of monoclonal gammopathy of undetermined significance and Bence Jones proteinuria, and a 44 year history of ankylosing spondylitis, developed a nephrotic syndrome secondary to renal amyloidosis. Clinically the amyloidosis was ascribed to Bence Jones proteinuria rather than to the burnt out ankylosing spondylitis. However, histochemical and immunofluorescence sta...
متن کاملBence Jones proteinuria and myeloma kidney.
Bence-Jones proteinuria refers to urinary excretion of monoclonal light chains. It results from exclusive production of one light chain, or the unbalanced synthesis of heavy and light chains, with the latter being in excess. Free Kor A-light chains are therefore excreted alone or in addition to complete immunoglobulin molecules carrying the same light chain type. Free light chains are low molec...
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ژورنال
عنوان ژورنال: Nihon Naika Gakkai Zasshi
سال: 1972
ISSN: 0021-5384,1883-2083
DOI: 10.2169/naika.61.759